Tag: aging

Lamotrigine, an anticonvulsant used to treat bipolar II disorder (cyclical depression without mania) has been shown to extend lifespan but induce motor retardation as a proxy for brain aging. Other anticonvulsants, including lithium and valproic acid (Depakote) have beneficial effects on both longevity and healthspan. “The discovery of life extension in Caenorhabditis elegans treated with…